Postdoctoral scientist in gene therapy immunology

Job description

·  Job facts

At Roche, we believe it's urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients' lives and we are fearless in both decision and action. And we believe that good business means a better world.

Roche Pharma Research and Early Development (pRED) translates extraordinary science into medical innovation through a diversity of technologies and talent. We deliver on individual patient needs through a deep understanding of disease biology and the implementation of Personalized Healthcare strategies.

pRED Pharmaceutical Sciences (PS) is a single Global Function, comprised of seven research units, spanning six sites across three continents, covering the areas of Investigative Safety; Project Leaders and Modeling & Simulation; Clinical Pharmacology and Bioanalytical R&D; Strategic Outsourcing, Operations and Externalization; Comparative Toxicology and Pharmacology; BiOmics and Pathology. In BiOmics (Biomarkers, Bioinformatics and Omics) and Pathology, we provide expert solutions to pRED projects by generating and integrating molecular, cellular, tissue and functional data.

As part of the Biomics department, the Immunosafety laboratory has the mission to assess the risk of new drug candidates to interfere with the immune system, including risks related to immunogenicity, hypersensitivity and immune function alteration.

Who you are:

We are looking for a highly motivated postdoctoral scientist who will work in close collaboration with scientists from different departments within PS to address the immunogenicity and immunosafety of AAV gene therapy vectors.

Your skillset should include:

·  Strong knowledge of immunology
·  Experience in the field of gene therapy, ideally with AAV vectors
·  Practical experience in primary cell culture and in vitro assays with immune system cells
·  Knowledge of flow cytometry is a must. Experience in ELISpot assays is a plus.
·  Excellent interpersonal and communication skills, with the ability to work both collaboratively and independently
·  Proficient in spoken and written English

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients' lives. If you want to work in a hardworking team, make your mark & improve lives, apply now!

What we stand for:

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Roche is an equal opportunity employer.
Research & Development, Research & Development > Research

·  Who we are

At Roche, 98,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an equal opportunity employer.

Desired profile

Who you are:

We are looking for a highly motivated postdoctoral scientist who will work in close collaboration with scientists from different departments within PS to address the immunogenicity and immunosafety of AAV gene therapy vectors.

Your skillset should include:

·  Strong knowledge of immunology
·  Experience in the field of gene therapy, ideally with AAV vectors
·  Practical experience in primary cell culture and in vitro assays with immune system cells
·  Knowledge of flow cytometry is a must. Experience in ELISpot assays is a plus.
·  Excellent interpersonal and communication skills, with the ability to work both collaboratively and independently
·  Proficient in spoken and written English

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking, then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients' lives. If you want to work in a hardworking team, make your mark & improve lives, apply now!

What we stand for:

Roche embraces diversity and equal opportunity in a serious way. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

Roche is an equal opportunity employer.
Research & Development, Research & Development > Research

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