The Autoimmunity & Type 1 Diabetes Cluster, within the Immunology & Inflammation Therapeutic Area, aims to discover new mechanistic pathways in autoimmune diseases and develop these findings into novel disease-modifying drugs that improve the lives of patients. Our focus is on inflammatory diseases driven by self-reactivity and characterized by loss of immunological tolerance. The current major emphasis is on systemic lupus erythematosus and type 1 diabetes, and may extend into other immune-mediated areas (such as multiple sclerosis, rheumatological and antibody-mediated diseases) when our science and discoveries lead us.
We wish to recruit a Scientist who will work alongside a team of 2-4 members in a laboratory team led by a Senior Principal Scientist, with the aim of identifying new disease targets and taking these through to drug development. Our target discovery process is facilitated by extensive collaboration across our other clusters (focused on Checkpoint Immunity, Type 2 Inflammation & Fibrosis, Type 1 and Type 17 Immunity and Precision Immunology) and our platforms in drug discovery, biologic molecules and disease models.
The successful candidate should have deep knowledge of immunology and demonstrated ability to integrate into projects/assignments as part of a team, contributing technical skills and functional knowledge. Evidence of technical expertise in T and B cell biology, immune regulation, immune tolerance and cytokine biology is expected, as well as experience of developing novel processes and hypotheses and finding solutions to technical or research questions. Candidate should be able to work under limited supervision and manage his/her time efficiently.
The successful candidate will join a Cluster that is committed to finding solutions to autoimmune diseases and comprises three other laboratory teams, each with senior scientific leadership and similar goals.
· Participate in programs through the implementation and performance of laboratory experiments to identify targets and develop molecules to interrupt pathways to autoimmune disease.
· Coordinate such studies with other lab and Autoimmunity Cluster members, and our colleagues in other Clusters and platforms.
· Build and maintain collaborative relationships and working across a matrix environment that includes partners in Translational Medicine, Clinical Development, Drug Metabolism & Pharmacokinetics and Medical Affairs to build a shared work plan and ensure alignment between stakeholders.
· Oral and written communication of projects and data packages to varied audiences.
· Maintain a thorough and up to date knowledge of scientific developments in our field and utilize this in our activities.
· Ensure productive and efficient utilization of department resources to meet project timelines.
· Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials such as controlled drug and radioactive compounds.
· Mentor/supervise non-PhD scientists in the Cluster and be accountable for the effective performance of the team and its individuals.
Basic qualifications and requirements include:
· Bachelor's degree in a relevant field with approximately 6 years of laboratory experience; or Master's degree and >3 years laboratory experience or PhD with minimal experience. Work experience should be in relevant scientific areas in academia or the biopharmaceutical industry.
· Demonstrated expertise in immunology, particularly related to autoimmunity and tolerance.
· Working knowledge and experience relevant to discovery and development of drugs and biologics.
· Excellent organizational and project management skills required.
· Ability to Interact well with a diverse group and maintain strong working relationships with internal and external collaborators.
· Effective writer and communicator of research or other regulatory materials.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.