Offers “Roche”

Expires soon Roche

Scientist - Technology

  • South San Francisco, USA
  • Chemistry / Biology / Agronomy

Job description

  Job facts

We are seeking a Scientist to support drug discovery in the Department of Small Molecule Pharmaceutics at Genentech. The primary responsibilities for this role extend from formulation and pharmaceutics support from early stage research to late stage research, IND-enabling safety studies, and informing development strategy for clinical formulation. This person will primarily be responsible for pharmaceutical profiling and drug delivery approaches during preclinical assessment of novel small molecule therapeutics for unmet medical needs.

The successful candidate is expected to:

·  Drive scientific and technical innovation collaboratively with other members of Discovery teams and within Small Molecule Pharmaceutical Sciences.
·  Focus on selection, profiling and advancing small molecule clinical candidates in a scientifically rigorous, phase-appropriate manner
·  Develop and execute pre-formulation and preclinical formulation strategies based on strong scientific rationale and pharmaceutical/biopharmaceutical properties of molecules for one or more projects
·  Based on preclinical knowledge, identify potential risks during clinical formulation development.
·  Leverage preclinical knowledge, participate in key decisions such as physical form selection and clinical formulation design
·  Have a proven track record of publication in high quality scientific journals
·  Participate and thrive in an interactive, collaborative, team-oriented culture, interfacing with discovery and early development functions

·  Who we are

A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.

If you have a disability and need an accommodation in connection with the on-line application process, please email us at .
EEO is the Law

PAY TRANSPARENCY NONDISCRIMINATION PROVISION
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c)

Desired profile

Who you are

In hiring new employees, we look for people who are also inspired by our mission and who would fit in well with the collaborative, rigorous and entrepreneurial spirit of the company culture. Because we know that employees are critical to our success in bringing novel medicines to patients, we are dedicated to remaining a great place to work and to providing employees with programs, services and benefits that allow them to bring the best to the business and to their personal lives.

A Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering or related fields with 3-8 years' experience in the pharmaceutical industry. Knowledge and expertise in the interplay between molecular physicochemical properties, absorption processes, and pharmacokinetic/pharmacodynamic (PK/PD) relationships with formulation modality is required. Experience in working within the drug discovery space is highly desired. Additionally, experience in alternative therapeutic modalities (such as peptides, etc.) and drug delivery technologies (such as inhalation, ocular, topical, etc.) is highly valued.

The successful candidate must have excellent communication skills, interpersonal skills,
and problem-solving skills, as well as demonstrate the ability to plan, design, implement and analyze laboratory experiments to advance projects and guide formulation selection and development.

*LI-gRED-MD2

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